3D Image-Guided Automatic Pipette Positioning for Single Cell Experiments in vivo

نویسندگان

  • Brian Long
  • Lu Li
  • Ulf Knoblich
  • Hongkui Zeng
  • Hanchuan Peng
چکیده

We report a method to facilitate single cell, image-guided experiments including in vivo electrophysiology and electroporation. Our method combines 3D image data acquisition, visualization and on-line image analysis with precise control of physical probes such as electrophysiology microelectrodes in brain tissue in vivo. Adaptive pipette positioning provides a platform for future advances in automated, single cell in vivo experiments.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2015